爱游戏app官方下载

生科院胡志刚副教授-郭志刚教授课题组在细胞死亡和非小细胞肺癌治疗研究取得重要进展

ZAIZHONGLIUXIBAONEI,DNASUNSHANGXIUFUNENGLIDETISHENGNENGGOUBANGZHUZHONGLIUXIBAODIKANGHUALIAOYAOWUDEZUOYONG,DAOZHIHUALIAOSHIXIAO。YINCI,KAIFADNASUNSHANGXIUFUGUANJIANMEIDEYIZHIJIJINXINGKANGZHONGLIUZHILIAOHUOLIANHEZHILIAO,JUYOUZHONGYAODELILUNHELINCHUANGYIYI。PARPYIZHIJISHIFDAPIZHUNDESHOULEIZHENDUIDNASUNSHANGXIUFUTUJINGDEKANGZHONGLIUYAOWU,QIZHUYAOYINGYONGZAIBRCAQUEXIANDERUXIANAI、LUANCHAOAIJIQIANLIEXIANAIDENGZHONGLIUZHILIAOZHONG,BINGQIEJIYUQIKANGZHONGLIUYUANLITICHULELIANHEZHISIDEGAINIAN。DANSHIGAILEIYAOWUSHANGCHUYUZHUANLIBAOHUQI,SUIRANJINRUWOGUOYIBAOYAOPINMULU,DANYIRANJIAGEANGGUI,QIEYINGYONGDEZHONGLIUZHILIAOFANWEIYOUXIAN。SUOYIXUYAOKAIFAXINXINGDEZHENDUIDNASUNSHANGXIUFUTUJINGDEKANGZHONGLIUYAOWU。

JINRI,SHENGKEYUANHUZHIGANG-GUOZHIGANGKETIZUYIDNAJIANJIQIECHUXIUFUTUJING(BER)ZHONGDEGUANJIANMEIAPE1WEIYANJIUDUIXIANG,LIYONGJISUANJIXUNISHAIXUANHESHIYANXIANGJIEHEDEFANGFA,KAIFALEYIZHONGYIAPE1WEIBADIANDEXIAOFENZIYIZHIJI,WEIFEIXIAOXIBAOFEIAIZHILIAOTIGONGLEQIANZAIYAOWUHEKAIFASILU。YANJIUCHENGGUOYI“Small-molecule inhibition of APE1 induces apoptosis, pyroptosis, and necroptosis in non-small cell lung cancer”WEITIFABIAOZAI《Cell Death & Disease》SHANG。《Cell Death & Disease》WEINatureCHUBANJITUANXIAZHIMINGDEXIBAOSIWANGJIZHONGLIUYANJIUXIANGGUANZHUANYEQIKAN。2021NIANJISHIYINGXIANGYINZIWEI8.11。

JIANJIQIECHUXIUFU(BER)ZAIDNASUNSHANGXIUFUZHONGFAHUIZHEZHONGYAOZUOYONG,APE1SHIBERTUJINGZHONGDEGUANJIANXIANSUMEI,FUZEWUPIAOLINGWEIDIAN(AP)DEQIECHU。YIBAODAODEZHICHU,APE1ZAIDUOZHONGZHONGLIU,RUFEIXIAOXIBAOFEIAI(NSCLC)ZHONGGAOBIAODABINGYUHUANZHEYUHOUCHAXIANGGUAN,ERYIZHIAPE1DEBIAODAKEZENGJIAXIBAONEIDEDNASUNSHANGJILEIJINERYOUDAOZHONGLIUXIBAODIAOWANG。YINCIAPE1BEIRENWEISHIEXINGZHONGLIUDEZHONGYAOBIAOZHIWUZHIYI,KEYIZUOWEIKAIFAKANGZHONGLIUYAOWUDEQIANZAIBADIAN。ZAIBENYANJIUZHONG,LIYONGYIZHONGGAOTONGLIANGDEJISUANJIXUNISHAIXUANJISHUJIEHETIWAISHENGHUASHIYAN,GENJUAPE1DANBAIDESANWEIJIEGOU,SHAIXUANCHUYIZHONGAPE1XIAOFENZIYIZHIJI。LIYONGGAIYIZHIJICHULINSCLCXIBAOXIA549HENCI-H460,TONGGUOMIANYIYINGGUANGHEHUIXINGTUOWEIDENGSHIYANZHENGMINGQINENGGOUYIZHIAPE1QIEGEMEIHUOXINGCONGERYOUDAOXIBAONEIDEDNASUNSHANGZENGJIA。JINYIBUDESHIYANSHIYONGBUTONGNONGDUDEGAIYIZHIJICHULIXIBAO,ZAIXIBAOXINGTAIXUEFENXIFAXIANQIKEYIDAOZHIA549HENCI-H460XIBAOCHUXIANBUTONGCHENGDUDEDIAOWANG、JIAOWANGHEHUAISI。ZAIDONGWUSHUIPING,TONGGUOGOUJIANNCI-H460XIAOSHUPIXIACHENGLIUMOXING,BIAOMINGGAIYIZHIJIYENENGGOUZUZHIFEIXIAOXIBAOFEIAIDEJINZHAN。ZHEIXIEFAXIANYANZHENGLEAPE1ZUOWEIFEIXIAOXIBAOFEIAIZHILIAOBADIANDEKENENGXING,BINGWEIBAXIANGZHILIAOFEIXIAOXIBAOFEIAIHEQITAAIZHENGDEGUANJIANDNAXIUFUDANBAIDEXIAOFENZIYAOWUDEKAIFATIGONGLEYANJIUCELVEHELILUNZHICHENG。

AIYOUXIappGUANFANGXIAZAI:APE1YIZHIJIYOUDAOFEIXIAOXIBAOFEIAIXIBAOSIWANGJIYIZHIZHONGLIUSHENGZHANG

NANJINGSHIFANDAXUESHENGMINGKEXUEXUEYUANSHUOSHIYANJIUSHENGLONGKAILI、LILULUJIBOSHIHOUGULILIWEILUNWENDEGONGTONGDIYIZUOZHE,GUOZHIGANGJIAOSHOUHEHUZHIGANGFUJIAOSHOUWEILUNWENDEGONGTONGTONGXUNZUOZHE,GAIYANJIUDEDAOLEGUOJIAZIRANKEXUEJIJIN、JIANGSUSHENGGAOXIAOZIRANKEXUEJIJINHEJIANGSUSHENGSHENGWUXUEYOUSHIXUEKEDENGXIANGMUDEZIZHU。

LUNWENLIANJIE:http://www.nature.com/articles/s41419-021-03804-7

  • 更新时间

    2021NIAN05YUE20RI 14:24

  • 阅读量

  • 供稿

    SHENGKEYUAN

  • 打印

南京市仙林大学城文苑路1号,
邮编 210023
sun@pinceldarte.com

Copyright © 南京师范大学 2020. All rights reserved.

分享到

爱游戏体育平台 - APP首頁 2021爱游戏app|下载 爱游戏app|下载 爱游戏app下载2021爱游戏app下载爱游戏app下载